{Reference Type}: Journal Article
{Author}: Huang, Qianfei; Chen, Sihang; Chen, Hao; Wang, Yuefei; Wang, Yiqi; Hochstetter, Danielle; Xu, Ping
{Year}: 2013
{Title}: Studies on the bioactivity of aqueous extract of pu-erh tea and its fractions: In vitro antioxidant activity and α-glycosidase inhibitory property, and their effect on postprandial hyperglycemia in diabetic mice
{URL}: http://www.sciencedirect.com/science/article/pii/S0278691512008460
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{Tag}: 0
{Star}: 0
{Journal}: Food and Chemical Toxicology
{Volume}: 53
{Issue}: 0
{Pages}: 75-83
{Date Displayed}: 2013/3//
{Alternate Title}: Food and Chemical Toxicology
{ISBN/ISSN}: 0278-6915
{Keywords}: Pu-erh tea extracts; Tea polysaccharides; Antioxidant activity; α-Glycosidase; Postprandial hyperglycemia
{Abstract}: Despite abundant research that has been carried out on the potential health benefits of pu-erh tea, no consensus till now, has been reached on which constituent is mainly responsible for its bioactivity. In this work, the aqueous extract (AE) and its fraction enriched with active constituents were prepared from pu-erh tea, and their bioactivities were investigated. It was found that tea polyphenols (TP), tea polysaccharides (TPS), caffeine (Caf), protein (Pro), amino acids (AA) were accumulated in several fractions after solvent extraction despite not being separated completely. Meanwhile, 95% ethanol precipitate (EP) and ethyl acetate fraction (EF) possessed remarkable antioxidant activity and potent inhibitory effects against α-glycosidase in vitro. Furthermore, all the extracts (50 mg/kg BW) showed a significant (p < 0.05) effect on postprandial hyperglycemia in diabetic mice as compared with a model group, and the suppression of EP was not significantly (p > 0.05) different from that of acarbose at the same dosage (50 mg/kg BW), which indicate that these fractions could be developed as potential anti-diabetic agents.

{Reference Type}: Journal Article
{Author}: Liu, Jun; Jia, Liang; Kan, Juan; Jin, Chang-hai
{Year}: 2013
{Title}: In vitro and in vivo antioxidant activity of ethanolic extract of white button mushroom (Aguricus bisporus)
{Tag}: 0
{Star}: 0
{Journal}: FOOD AND CHEMICAL TOXICOLOGY
{Volume}: 51
{Pages}: 310-316
{ISBN/ISSN}: 0278-6915
{Keywords}: WILD EDIBLE MUSHROOMS; AGARICUS-BISPORUS; CULTIVATED MUSHROOMS; MEDICINAL MUSHROOMS; POLYSACCHARIDES; DISEASE; STRESS; TURKEY; MICE; Agaricus bisporus; Antioxidant activity; Ethanolic extract; In vitro; In vivo; Phenolic compounds
{Abstract}: The antioxidant activities of ethanolic extract from edible mushroom Agaricus bisporus (A. bisporus) were evaluated by various methods in vitro and in vivo. In antioxidant assays in vitro, ethanolic extract of A. bisporus was found to have strong reducing power, superoxide radical, hydroxyl radical and 2,2-diphenyl-1-piaylhydrazyl radical scavenging activity, and moderate hydrogen peroxide scavenging activity. In antioxidant assays in vivo, mice were administered with ethanolic extract of A. bisporus via gavage for 30 consecutive days. As a result, administration of ethanolic extract significantly enhanced the activities of antioxidant enzymes in serums, livers and hearts of mice. In addition, the total phenolic content in the extract determined by Folin-Ciocalteu method was 6.18 mg of gallic acid equivalents per gram of dry weight. The main phenolic compounds in ethanolic extract analyzed by ultra-high performance liquid chromatography tandem mass spectrometry were determined as gallic acid, protocatechuic acid, catechin, caffeic acid, ferulic acid and myricetin. These results suggested that ethanolic extract of A. bisporus had potent antioxidant activity and could be explored as a novel natural antioxidant. (C) 2012 Elsevier Ltd. All rights reserved.
{Author Address}: Yangzhou Univ, Coll Food Sci & Engn, Yangzhou 225127, Jiangsu, Peoples R China; Yangzhou Univ, Coll Food Sci & Engn, Yangzhou 225127, Jiangsu, Peoples R China; Yangzhou Univ, Coll Food Sci & Engn, Yangzhou 225127, Jiangsu, Peoples R China; Yangzhou Univ, Coll Food Sci & Engn, Yangzhou 225127, Jiangsu, Peoples R China
{Database Provider}: Web of Science SCI
{Language}: English
{Country}: Peoples R China

{Reference Type}: Journal Article
{Author}: Dong, Jing Z.; Ding, J.; Yu, Pei Z.; Lei, Can; Zheng, Xiao J.; Wang, Y.
{Year}: 2013
{Title}: Composition and distribution of the main active components in selenium-enriched fruit bodies of Cordyceps militaris link
{Tag}: 0
{Star}: 0
{Journal}: FOOD CHEMISTRY
{Volume}: 137
{Issue}: 1-4
{Pages}: 164-167
{ISBN/ISSN}: 0308-8146
{Keywords}: LIQUID CULTURE; ANTIOXIDANT; PLANTS; POLYSACCHARIDE; MECHANISMS; EXTRACTION; GROWTH; CANCER; Cordyceps militaris; Selenocompounds; Distribution; Active components; Minerals
{Abstract}: Selenium-enriched Cordyceps militaris fruit bodies are industrially cultivated as functional food or medicinal food in China and southeast Asia. However, composition of selenium compounds and distribution of the main bioactive components are still unknown. In the selenium-enriched fruit bodies, the main soluble selenium compounds of low molecular weight were identified as SeMet (selenomethionine), and the main selenium compounds bound in proteins were identified as SeMet and SeCys (methylselenocysteine). Trace minerals as Se (selenium), Zn (zinc), Fe (iron) and the main active components as adenosine, cordycepin and carotenoids were mostly distributed in the terminal of fruit bodies, while P (phosphorus) and K (potassium) were evenly distributed in the fruit bodies. The results indicated that terminal of the fruit bodies should be the better materials for production of advanced functional food. So cultivation of relatively short and thick fruit bodies with bigger terminals deserves further research. Crown Copyright (C) 2012 Published by Elsevier Ltd. All rights reserved.
{Author Address}: Hubei Univ Nationalities, Key Lab Biol Resources Protect & Utilizat Hubei P, Sch Biol Sci & Technol, Enshi 445000, Peoples R China; Hubei Univ Nationalities, Key Lab Biol Resources Protect & Utilizat Hubei P, Sch Biol Sci & Technol, Enshi 445000, Peoples R China; Hubei Univ Nationalities, Key Lab Biol Resources Protect & Utilizat Hubei P, Sch Biol Sci & Technol, Enshi 445000, Peoples R China; Hubei Univ Nationalities, Key Lab Biol Resources Protect & Utilizat Hubei P, Sch Biol Sci & Technol, Enshi 445000, Peoples R China; Hubei Univ Nationalities, Key Lab Biol Resources Protect & Utilizat Hubei P, Sch Biol Sci & Technol, Enshi 445000, Peoples R China; Chinese Acad Sci, Key Lab Pant Germplasm Enhancement & Special Agr, Wuhan Bot Garden, Wuhan 430074, Peoples R China
{Database Provider}: Web of Science SCI
{Language}: English
{Country}: Peoples R China; Peoples R China

{Reference Type}: Journal Article
{Author}: Han, Zi-Hua; Ye, Jian-Min; Wang, Guan-Fu
{Year}: 2013
{Title}: Evaluation of in vivo antioxidant activity of Hericium erinaceus polysaccharides
{Tag}: 0
{Star}: 0
{Journal}: INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
{Volume}: 52
{Pages}: 66-71
{ISBN/ISSN}: 0141-8130
{Keywords}: ISCHEMIA-REPERFUSION INJURY; LIPID-PEROXIDATION PRODUCTS; OXIDATIVE DAMAGE; NEUTROPHIL INFILTRATION; KIDNEY; RATS; ACID; Hericium erinaceus polysaccharides; Kidney; Ischemia reperfusion; SOD; HPLC; Antioxidant
{Abstract}: Hericium erinaceus polysaccharide (HEP) is a traditional Chinese medicine. In the present study, chemical composition and antioxidant activity of HEP was investigated. HPLC analysis showed that the HEP was composed of xylose (7.8%), ribose (2.7%), glucose (68.4%), arabinose (11.3%), galactose (2.5%) and mannose (5.2%). HEP was pre-administered to mice by gavage at a dose of 300 mg/kg for 15 days. Results found that HEP preadministration resulted in a significant decline in blood urea nitrogen (BUN), serum creatinine (Scr) and increase in creatinine clearance (CrCI) levels in HEP-pretreated group compared to renal ischemia reperfusion (IR) group. Malondialdehyde (MDA) level significantly increased, whereas Level of reduced glutathione (GSH) markedly decreased in renal IR animals. These results indicate that IR induced renal oxidative injury damage, as indicated by a increase in MDA level, and decrease in GSH level as well as the antioxidant enzymes activity. Such effects reflect that HEP can significantly decrease lipid peroxidation level and increase antioxidant enzymes activities in experimental animals. (C) 2012 Elsevier B.V. All rights reserved.
{Author Address}: Taizhou Enze Med Ctr Grp, Dept Urol, Luqiao Hosp, Taizhou 318050, Zhejiang, Peoples R China; Taizhou Enze Med Ctr Grp, Dept Urol, Luqiao Hosp, Taizhou 318050, Zhejiang, Peoples R China; Taizhou Enze Med Ctr Grp, Dept Urol, Luqiao Hosp, Taizhou 318050, Zhejiang, Peoples R China
{Database Provider}: Web of Science SCI
{Language}: English
{Country}: Peoples R China